FLUIDS FOR RESUSCITATION

Resuscitation fluids.

From the University of New South Wales, the Division of Critical Care and Trauma, George Institute for Global Health, and the Department of Intensive Care Medicine, St. George Hospital — all in Sydney (J.A.M.); and the National Institute for Health Research, University College London Hospitals Biomedical Research Centre, London (M.G.M.). Address reprint requests to Dr. Myburgh at the Department...

Hemoglobin-based oxygen-carrying resuscitation fluids.

Anti-inflammatory adjuvant in resuscitation fluids improves survival in hemorrhage.

OBJECTIVES Severe hemorrhage is a common cause of death despite the recent advances in critical care. Conventional resuscitation fluids are designed to reestablish tissue perfusion, but they fail to prevent lethal inflammatory responses. Our previous studies indicate that ethyl pyruvate (EP) inhibits tumor necrosis factor (TNF) production from macrophages. Here, we analyze whether EP can provid...

Choice of fluids for resuscitation in children with severe infection and shock: systematic review

OBJECTIVE To systemically review the evidence from clinical trials comparing the use of crystalloids and colloids for fluid resuscitation in children with severe infection. DATA SOURCES Medline (1950-2008), PubMed, the Cochrane Library, Embase (1980-2008), and reference lists. Eligibility criteria Published studies comparing fluid resuscitation with crystalloid or colloidal solutions in sever...

Albumin versus Other Fluids for Fluid Resuscitation in Patients with Sepsis: A Meta-Analysis

BACKGROUND Early fluid resuscitation is vital to patients with sepsis. However, the choice of fluid has been a hot topic of discussion. The objective of this study was to evaluate whether the use of albumin-containing fluids for resuscitation in patients with sepsis was associated with a decreased mortality rate. METHODS We systematically searched PubMed, EMBASE and Cochrane library for eligi...